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The concentrations of IGF-I and IGF-II protein are expressed as the ratio of IGF protein (nanograms or micrograms) to total protein (milligrams) in the homogenates of muscle tissue. IGF-I is the only known protein to induce an increase in muscle muscle thickness; IGF-II is the only found in IGF-I-deficient animals. While these two proteins are not in high enough concentrations to stimulate collagen synthesis and thus, stimulate the formation of tendon, their excess levels are not adequate to induce the synthesis of collagen but rather, can stimulate the formation of an additional protein, fibroblasts (the precursor cells for the production of tendon), buy anabolic steroids online paypal. This type of collagen-stimulating compound termed the fibroblast growth factor system (FGF).Inhibition of collagen synthesis is one of the mechanisms by which the growth plate induces tendon growth and tendon rupture, bsn protein crisp. Many different molecules stimulate the synthesis of collagen. One of them is IGF-I. IGF-I has been shown to be associated with both muscle cell hyperplasia and tendon hyperplasia, bsn crisp protein. IGF-I is involved in the activation of two different receptor families, transforming growth factor-beta and insulin-like growth factor 2 (IGF-1) receptors (Gagnon & Todorov, 1996), buy anabolic steroids online ireland. A growing body of evidence indicates that IGF-I activates these two receptors (Lamberg & Jansson, 1993; Brescia et al., 1992). The primary function of IGF-I is primarily to activate the TGF beta receptor (Treg), a transcription factor that is found on fibroblasts and thus initiates the induction of proliferation (Wolff, 1999), buy anabolic steroids online in india. The second function of IGF-I was previously discussed. This is to induce insulin-like growth factor 2 (IGF-2). IGF-2 is also a potent inhibitor of collagen type I-II synthesis and also promotes type II collagen synthesis, buy anabolic steroids online forum. In fact, IGF-2 stimulates the activation of both Treg and IGF-1 receptor isoforms. In turn, the activation of these two receptors is necessary to induce the synthesis of collagen. However, as noted, this is primarily the function of IGF-I, as it can be activated by almost any substance with this mechanism(Rau et al, buy anabolic steroids online paypal., 1984), buy anabolic steroids online paypal. It is also possible that IGF-2 promotes tendon growth primarily by facilitating IGF-1 receptor activation.Both IGF-I and IGF-2 promote tendon growth by acting on the growth plate, buy anabolic steroids online in india. They stimulate the growth plate to induce the growth of hypertrophic fibers.